In about half of all patients with rare hereditary disorders, it is still unclear what exact position of the genome is responsible for their condition. One reason for this is the enormous quantity of information encoded in human genes. Scientists ...
Read More »Characterization of circular RNAs with RNA-Seq
Deep sequencing techniques and advanced data analysis methods recently enabled the characterization of thousands of circular RNA isoforms (circRNAs) from a number of tissues and organisms. There is emerging evidence that some circRNAs may have important biological functions or serve ...
Read More »8th international Gene Quantification Event
qPCR dPCR & NGS 2017 Liquid Biopsy, Integrative Big Data Analysis, Biomarker Signature … and beyond Symposium & Industrial Exhibition & Application Workshops 3 – 7 April 2017, in Freising-Weihenstephan, School of Life Sciences, Technical University of Munich, Weihenstephan, ...
Read More »Recommendations for differential expression analysis and biomarker discovery small RNA-Seq experiments in an age of liquid biopsies
Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA (miRNA), from liquid biopsies additionally provides exciting possibilities for molecular diagnostics, and might help establish disease-specific biomarker signatures. ...
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