Histopathology-based staging of colorectal cancer (CRC) has utility in assessing the prognosis of patient subtypes, but as yet cannot accurately predict individual patient’s treatment response. Transcriptomics approaches, using array based or next generation sequencing (NGS) platforms, of formalin fixed paraffin ...
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Sequencing the nucleic acid content of individual cells or specific biological samples is becoming increasingly common. This drives the need for robust, scalable and automated library preparation protocols. Furthermore, an increased understanding of tissue heterogeneity has lead to the development ...
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Recent studies on single cells and population transcriptomics have revealed striking differences in global gene expression distributions. Single cells display highly variable expressions between cells, while cell populations present deterministic global patterns. The mechanisms governing the reduction of transcriptome-wide variability ...
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RNA-Seq Blog Transcriptome Research & Industry News
