RNA transcripts circulating in peripheral blood represent an important source of non-invasive biomarkers. To accurately quantify the levels of circulating transcripts, one needs to normalize the data with internal control reference genes, which are detected at relatively constant levels across ...
Read More »BADGE – A novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data
Recent advances in RNA sequencing (RNA-Seq) technology have offered unprecedented scope and resolution for transcriptome analysis. However, precise quantification of mRNA abundance and identification of differentially expressed genes are complicated due to biological and technical variations in RNA-Seq data. Researchers ...
Read More »RNA-Seq Blog – Poll Results
We asked: Which step of an RNA-Seq experiment is the greatest source of technical variability? Thanks to everyone who participated! Check out the new poll question in the narrow sidebar and cast your vote.
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