These multi-disciplinary studies will include the comprehensive analysis of RNA-seq and small RNA sequencing data. In addition to expertise in NGS data analysis, Ideal candidates will have extensive experience in Drosophila genetics. The successful candidate...
Read More »RNA Sequencing leads to stem cell break-through in bone growth
Human stem cells have shown potential in medicine as they can transform into various specialized cell types such as bone and cartilage cells. The current approach to obtain such specialized cells is to subject stem cells to specialized instructive protein ...
Read More »BoolFilter – an R package for estimation and identification of partially-observed Boolean dynamical systems
Gene regulatory networks govern the function of key cellular processes, such as control of the cell cycle, response to stress, DNA repair mechanisms, and more. Boolean networks have been used successfully in modeling gene regulatory networks. In the Boolean network ...
Read More »SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets
Although the number of RNA-Seq datasets deposited publicly has increased over the past few years, incomplete annotation of the associated metadata limits their potential use. Now, Texas A&M University researchers constructed a database by curating datasets related with RNA splicing ...
Read More »ASplice – a scalable and memory-efficient algorithm for de novo transcriptome assembly of non-model organisms
With increased availability of de novo assembly algorithms, it is feasible to study entire transcriptomes of non-model organisms. While algorithms are available that are specifically designed for performing transcriptome assembly from high-throughput sequencing data, they are very memory-intensive, limiting their ...
Read More »How to Analyze RNA-Seq Data?
This is a class recording of VTPP 638 “Analysis of Genomic Signals” at Texas A&M University. No RNA-Seq background is needed, and it comes with a lot of free resources that help you learn how to do RNA-seq analysis. You ...
Read More »RNASeqMetaDB – a database and web server for navigating metadata of publicly available mouse RNA-Seq data sets
Gene targeting is a protocol for introducing a mutation to a specific gene in an organism. Because of the importance of in vivo assessment of gene function and modeling of human diseases, this technique has been widely adopted to generate ...
Read More »Students at NCTR work on the development of bioinformatics and statistical methods for RNA sequencing data
By Nysia George, Ph.D., and Tom Powers Practical, hands-on laboratory work is important for all college students who want to become scientists—but, for many of them, such experiences are out of reach.That’s one of the reasons why every summer, our ...
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