Biomolecular engineer Todd Lowe has received a $2.7 million grant from the National Institutes of Health to support his lab’s international leadership...
Read More »MINTmap – profiling nuclear and mitochondrial tRNA fragments from short RNA-Seq data
Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly facilitated the study of tRFs. However, the repeat nature of the tRNA templates and the ...
Read More »Capture, Unfolding, and Detection of Individual tRNA Molecules Using a Nanopore Device
Transfer RNAs (tRNA) are the most common RNA molecules in cells and have critical roles as both translators of the genetic code and regulators of protein synthesis. As such, numerous methods have focused on studying tRNA abundance and regulation, with ...
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