The transcriptome is composed of different types of RNA molecules including mRNAs, tRNAs, rRNAs, and other noncoding RNAs that are found inside a cell at a given time. Analyzing transcriptome patterns can shed light on the functional state of the ...
Read More »RNA-Seq reveals previously unsuspected properties for two distinct categories of regulatory RNAs
The production of microRNA isoforms in human tissues depends on a person’s gender, population origin, and race as well as on tissue, disease and disease subtype Researchers at Thomas Jefferson University previously reported that miRNA isoforms in healthy individuals change as ...
Read More »New Family of Small RNAs Boosts Cell Proliferation in Cancer
(PHILADELPHIA) – Since their discovery in the 1950s, transfer RNAs (tRNAs) have been best known for their role in helping the cell make proteins from messenger RNA templates. However, recent studies have led to a previously-unsuspected concept that tRNAs are ...
Read More »FlaiMapper – computational annotation of small ncRNA derived fragments using RNA-seq high throughput data
Recent discoveries show that most types of small non-coding RNAs (sncRNAs) such as miRNAs, snoRNAs and tRNAs get further processed into putatively active smaller RNA species. Their roles, genetic profiles and underlying processing mechanisms are only partially understood. To find ...
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