Using Single Nucleotide Variations in Single-Cell RNA-Seq to Identify Tumor Subpopulations and Genotype-phenotype Linkage

March 9, 2017 Leave a comment 5,785 Views

Despite its popularity, characterization of subpopulations with transcript abundance is subject to significant amount of noise. Researchers at the University of Hawaii Cancer Center propose to use effective and expressed nucleotide variations (eeSNVs) from scRNA-seq as alternative features for tumor subpopulation ...

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Tag Archives: tumor subpopulations

Using Single Nucleotide Variations in Single-Cell RNA-Seq to Identify Tumor Subpopulations and Genotype-phenotype Linkage

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