Structural variants (SVs) may be an underestimated cause of hereditary cancer syndromes given the current limitations of short-read next-generation sequencing. Here researchers from the University of...
Read More »MEA – an integrated allele-specific pipeline for methylomic and epigenomic analysis
Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and specific histone...
Read More »RNA-Seq reveals the long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications
To date, a comprehensive characterization of the dynamic landscape of lncRNAs during the neuroendocrine transdifferentiation (NEtD) process has not been performed. A temporal analysis of the...
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