Tag Archives: University of Kansas Medical Center

Quality control, global biases, normalization, and analysis methods for RNA-Seq data are quite different than those for microarray-based studies. The assumption of normality is reasonable for microarray based gene expression data; however, RNA-Seq data tend to follow an over-dispersed Poisson ...

Advances in next-generation DNA sequencing technologies are now enabling detailed characterization of sequence variations in cancer genomes. With whole genome sequencing...

Cancer is a generic term for a large group of malignant diseases that can affect any part of the body. It is characterized by invasive, abnormal growth which grows beyond the usual boundaries and spreads to adjoining or distant organs ...