University of Kentucky researchers have developed SeqOthello, an ultra-fast and memory-efficient indexing structure to support arbitrary sequence query against large collections of RNA-seq...
Read More »iMapSplice – Alleviating reference bias through personalized RNA-seq alignment
Genomic variants in both coding and non-coding sequences can have functionally important and sometimes deleterious effects on exon splicing of gene transcripts. For transcriptome profiling using RNA-seq, the accurate alignment of reads across exon...
Read More »Scientists use RNA-Seq to discover unexpected functions of snoRNAs
Small nucleolar RNAs play a role in the development of some diseases An international team of researchers has discovered unexpected functions of small nucleolar RNAs (snoRNAs) that explains the cause of some diseases. The research, led by Prof. Stefan Stamm ...
Read More »Interesting Times in RNA Sequencing
A multi-institution research group jointly led by Professor Jan Prins and UNC CS alumna Professor Jinze Liu at the University of Kentucky is developing algorithms and software to analyze RNA using high-throughput sequencers. The software is in use in multiple ...
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