Sequencing data has become a standard measure of diverse cellular activities. For example, gene expression is accurately measured by RNA sequencing (RNA-Seq) libraries, protein-DNA interactions are...
Read More »RNA-Seq reveals immune cells mistake heart attacks for viral infections
A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic ...
Read More »DNApi – A De Novo Adapter Prediction Algorithm for Small RNA Sequencing Data
With the rapid accumulation of publicly available small RNA sequencing datasets, third-party meta-analysis across many datasets is becoming increasingly powerful. Although removing the 3´ adapter is an essential step for small RNA sequencing analysis, the adapter sequence information is not ...
Read More »Tailor – a computational framework for detecting non-templated tailing of small silencing RNAs
Small silencing RNAs, including microRNAs, endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), have been shown to play important roles in fine-tuning gene expression, defending virus and controlling transposons. Loss of small silencing RNAs or components in their pathways ...
Read More »Post-doc Position Available – Bioinformatics and Integrative Biology
Institution – University of Massachusetts Medical School Web Address – http://www.umassmed.edu Location – Worcester Responsibilities – A postdoctoral associate position is available in Dr. Konstantin Zeldovich-s laboratory in the Program in Bioinformatics and Integrative Biology. The postdoctoral associate will work ...
Read More »An efficient and sensitive method for preparing cDNA libraries from scarce biological samples
The preparation and high-throughput sequencing of cDNA libraries from samples of small RNA is a powerful tool to quantify known small RNAs (such as microRNAs) and to discover novel RNA species. Interest in identifying the small RNA repertoire present in ...
Read More »