The ability to quantify cellular heterogeneity is a major advantage of single-cell technologies. However, statistical methods often treat cellular heterogeneity as a nuisance. Researchers from the Dana-Farber Cancer Institute and the University of Wisconsin, Madison present a novel method to ...
Read More »University of Wisconsin researchers study toxic effects with RNA-Seq of miniature brain mimics
from Chemical & Engineering News by Britt E. Erickson Scientists in Wisconsin have succeeded in growing three-dimensional brainlike tissue structures derived from human embryonic stem cells. Unlike previous miniature model brains, the new structures can be easily reproduced and they contain ...
Read More »RSEM-EVAL – for evaluating assemblies when the ground truth is unknown
De novo RNA-Seq assembly facilitates the study of transcriptomes for species without sequenced genomes, but it is challenging to select the most accurate assembly in this context. To address this challenge, a team led by researchers at the University of ...
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