VDJPuzzle – B-cell receptor reconstruction from single-cell RNA-seq

April 18, 2018 Leave a comment 5,291 Views

The B-cell receptor (BCR) performs essential functions for the adaptive immune system including recognition of pathogen-derived antigens. The vast repertoire and adaptive variation of BCR sequences due to V(D)J recombination and somatic...

Researchers devise a new method to study T cell heterogeneity from single cell RNA-seq data

February 17, 2016 Leave a comment 5,116 Views

Heterogeneity of T cells is a hallmark of a successful adaptive immune response, harnessing the vast diversity of antigen-specific T cells into a coordinated evolution of effector and memory outcomes. The T cell receptor (TCR) repertoire is highly diverse to ...

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Tag Archives: UNSW

VDJPuzzle – B-cell receptor reconstruction from single-cell RNA-seq

Researchers devise a new method to study T cell heterogeneity from single cell RNA-seq data

CircAID-p-seq – a PCR-free library preparation for selective 3′ phospho-RNA sequencing

Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs

CLEARER – a machine learning approach for predicting essential genes across eukaryotes

scRNA-Seq reveals how genetic ancestry shapes immune response to influenza virus

Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistance

Microwell-seq – high-throughput screening with single-cell transcriptional profiling

Postdoc position available – computational biology: tumour heterogeneity and resistance mechanisms