VDJPuzzle – B-cell receptor reconstruction from single-cell RNA-seq

April 18, 2018 Leave a comment 4,683 Views

The B-cell receptor (BCR) performs essential functions for the adaptive immune system including recognition of pathogen-derived antigens. The vast repertoire and adaptive variation of BCR sequences due to V(D)J recombination and somatic...

Researchers devise a new method to study T cell heterogeneity from single cell RNA-seq data

February 17, 2016 Leave a comment 4,828 Views

Heterogeneity of T cells is a hallmark of a successful adaptive immune response, harnessing the vast diversity of antigen-specific T cells into a coordinated evolution of effector and memory outcomes. The T cell receptor (TCR) repertoire is highly diverse to ...

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Tag Archives: UNSW

VDJPuzzle – B-cell receptor reconstruction from single-cell RNA-seq

Researchers devise a new method to study T cell heterogeneity from single cell RNA-seq data

A robust method of nuclei isolation for single-cell RNA sequencing of solid plant tissues

Zymo Research releases bioinformatics pipeline for SARS-CoV-2 variant detection

Integrating barcoded neuroanatomy with spatial transcriptional profiling

Single-cell map of early stage lung cancer and normal lung sheds light on tumor development, new therapeutic targets

Performance assessment of sample-specific network control methods for bulk and single-cell biological data analysis

Single-nucleus RNA sequencing explains why some neurons are more susceptible than others in Alzheimer’s disease

RNA-Seq data suggests that exitron splicing represents an additional cancer-driving mechanism beyond genetic alterations