Thinking Inside The Box – Insights Into One Of The World’s Deadliest Venoms from discovermagazine. com by Christie Wilcox When you get right down to it, box jellyfish are little more than goo. The majority of their volume is mesoglea, a ...
Read More »The evolution of black widow venom
Black widow venom contains α-latrotoxin, infamous for causing intense pain. Combining 33kb of Latrodectus hesperus genomic DNA with RNA-Seq, we characterized the α-latrotoxin gene and discovered a paralog, 4.5kb downstream. Both paralogs exhibit venom gland specific transcription, and may be ...
Read More »Black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics
Animal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries. Next-generation transcriptomics and proteomics provide unparalleled, but underexploited, capabilities for venom characterization. A team led by researcher at the University of Massachusetts ...
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