For the first time, scientists at the Federal University of São Paulo (UNIFESP) in Brazil have shown that infection by SARS-CoV-2, the virus that causes COVID-19, changes the functioning of host cell RNA. They arrived at this conclusion by analyzing ...
Read More »An application of RNA sequencing toward mRNA based nanotherapeutics against SARS-CoV-2 infections
Due to fast transmission and various circulating SARS-CoV-2 variants, a significant increase of coronavirus 2019 infection cases with acute respiratory symptoms has prompted worries about the...
Read More »Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs
The SARS-CoV-2 virus has a complex transcriptome characterised by multiple, nested sub genomic RNAs used to express structural and accessory proteins. Long-read sequencing technologies such as nanopore...
Read More »scRNA-Seq can define host and viral transcriptional activity at the site of infection
Influenza A virus (IAV) and SARS-CoV-2 are pandemic viruses causing millions of deaths, yet their clinical manifestations are distinctly different...
Read More »Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in the lungs
Detailed knowledge about the dynamics of SARS-CoV-2 infection is important for uncovering the viral and host factors that contribute to COVID-19 pathogenesis. Old-World nonhuman primates recapitulate mild to moderate cases of COVID-19, thereby...
Read More »Researchers use single cell RNA sequencing to identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection. Researchers at MIT; the Ragon...
Read More »Theragen Etex develops sensitive RNA sequencing system to analyze COVID-19 RNA
Unlike the existing diagnostic kits that detect three genes from the Covid-19 virus, Theragen Etex’s newly developed system can reveal 30,000 ribonucleic acid sequences of Covid-19, the company said. SARS-CoV-2, the virus responsible...
Read More »Uniform analysis of coronavirus and SARS-COV-2 nanopore direct RNA sequencing datasets
Researchers from the Centre for Genomic Regulation (CRG) have launched a new database to advance the international research efforts studying COVID-19. The publicly-available, free-to-use resource (https://covid.crg.eu) can be used by researchers from around the world to study how different variations of the ...
Read More »VirusDetect – a new pipeline for virus identification
Researchers studying the viruses that affect agricultural production or human health now have a new tool for investigating where viruses have spread, on a local, national, or even global scale. VirusDetect is a free, open-source bioinformatics pipeline that can efficiently ...
Read More »Researchers employ RNA-Seq to monitor the diversity of viruses affecting animal health
The porcine reproductive and respiratory syndrome (PRRS) virus mutates rapidly, especially European strains, creating a challenge for diagnostic laboratories to monitor the disease. Today, Thermo Fisher Scientific presented research at the Pig Veterinary Society (IPVS) Congress showing the genetic diversity ...
Read More »