The BioBox Platform is cloud-based data analytics platform for scientists working with next-generation sequencing data. The platform enables scientists to easily access the data they want to work with and leverage in-platform tools to process, analyze and explore that data. ...
Read More »PieParty: Visualizing cells from scRNA-seq data as pie charts
Single cell RNA sequencing (scRNA-seq) has been a transformative technology in many research fields. Dimensional reduction techniques such as UMAP and tSNE are used to visualize scRNA-seq data in two or three dimensions in order for cells to be clustered ...
Read More »A quantitative framework for evaluating single-cell data structure preservation by dimensionality reduction techniques
High-dimensional data, such as those generated by single-cell RNA sequencing (scRNA-seq), present challenges in interpretation and visualization. Numerical and computational methods for dimensionality reduction allow for low-dimensional representation of...
Read More »MIRIA – a webserver for statistical, visual and meta-analysis of RNA editing data in mammals
Adenosine-to-inosine RNA editing can markedly diversify the transcriptome, leading to a variety of critical molecular and biological processes in mammals. Over the past several years, researchers have developed several new pipelines and software packages to identify RNA editing sites with ...
Read More »ShinyOmics – collaborative exploration of omics-data
Omics-profiling is a collection of increasingly prominent approaches that result in large-scale biological datasets, for instance capturing an organism’s behavior and response in an...
Read More »BISR-RNAseq – an efficient and scalable RNAseq analysis workflow with interactive report generation
RNA sequencing has become an increasingly affordable way to profile gene expression patterns. Here researchers from the Ohio State University introduce a workflow implementing several open-source softwares that can be run on a high...
Read More »Visualization methods for differential expression analysis
Despite the availability of many ready-made testing software, reliable detection of differentially expressed genes in RNA-seq data is not a trivial task. Even though the data collection is considered...
Read More »GenePattern Notebook for analysis and exploration of single-cell transcriptomic data
Single-cell RNA sequencing (scRNA-seq) has emerged as a popular method to profile gene expression at the resolution of individual cells...
Read More »Upcoming Workshop – RNA-Seq data analysis with Galaxy for clinical applications
From 2019-09-08 to 2019-09-08 - In this training course, we provide a summary of the applications of Next Generation Sequencing (NGS) technologies in the clinical context. These are presented through a hands-on session on RNA-Seq data analysis, following...
Read More »seqclusterViz – visualization of the small RNA transcriptome
The study of small RNAs provides us with a deeper understanding of the complexity of gene regulation within cells. Of the different types of small RNAs, the most important in mammals are miRNA, tRNA fragments and piRNAs. Using small RNA-seq ...
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