RNA-sequencing (RNA-seq) and microarrays are methods for measuring gene expression across the entire transcriptome. Recent advances have made these techniques practical and affordable for essentially any laboratory with experience in molecular biology. A variety of computational methods have been developed ...
Read More »Introduction to RNA Sequencing
From the 2016 Informatics for RNA-Seq Analysis workshop hosted by the Canadian Bioinformatics Workshops. This lecture is by Malachi Griffith from Washington University School of Medicine.
Read More »Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser
Advances in next-generation sequencing platforms have reshaped the landscape of functional genomic and epigenomic research as well as human genetics studies. Annotation of noncoding regions in the genome with genomic and epigenomic data has facilitated the generation of new, testable ...
Read More »Transcriptome sequencing uncovers altered long intergenic non-coding RNAs
Long intergenic non-coding RNAs (lncRNAs) represent an emerging and under-studied class of transcripts that play a significant role in human cancers. Due to the tissue- and cancer-specific expression patterns observed for many lncRNAs it is believed that they could serve ...
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