Gene fusions often occur in cancer cells and in some cases are the main driver of oncogenesis. Correct identification of oncogenic gene fusions thus has implications for targeted cancer therapy. Recognition of this potential has led to the development of ...
Read More »Granatum – the user-friendly web tool for single cell RNA sequencing analysis
Single-cell RNA sequencing (scRNA-seq) is a frontier research area that studies genomic events down to the individual cell level, providing unprecedented insights into many biological and medical questions, such as cancer heterogeneity and tumor...
Read More »RefEx – a reference gene expression dataset as a web tool for the functional analysis of genes
A large variety of data of life science (such as gene expression) is accumulated in the public database, but it is difficult to use. A web tool RefEx can easily search gene expression data available in public databases to obtain ...
Read More »Analyzing and interpreting genome data at the network level with ConsensusPathDB
ConsensusPathDB consists of a comprehensive collection of human (as well as mouse and yeast) molecular interaction data integrated from 32 different public repositories and a web interface featuring a set of computational methods and visualization tools to explore these data. ...
Read More »Heat*seq – an interactive web tool for high-throughput sequencing experiment comparison with public data
Better protocols and decreasing costs have made high-throughput sequencing experiments now accessible even to small experimental laboratories. However, comparing one or few experiments generated by an individual lab to the vast amount of relevant data freely available in the public ...
Read More »RAP – RNA-Seq Analysis Pipeline, a new cloud-based NGS web application
The study of RNA has been dramatically improved by the introduction of Next Generation Sequencing platforms allowing massive and cheap sequencing of selected RNA fractions, also providing information on strand orientation (RNA-Seq). The complexity of transcriptomes and of their regulative ...
Read More »AtCAST3.0 Update – A web-based tool for analysis of transcriptome data by searching similarities in gene expression profiles
In transcriptome experiments, the experimental conditions (e.g., mutants and/or treatments) cause transcriptional changes. Identifying experimental conditions that induce similar or opposite transcriptional changes can be used to identify experimental conditions that affect the same biological process. AtCAST is a web-based ...
Read More »