Tag Archives: Wellcome Trust Sanger Institute

SC3 – consensus clustering of single-cell RNA-Seq data

Using single-cell RNA-seq (scRNA-seq), the full transcriptome of individual cells can be acquired, enabling a quantitative cell-type characterisation based on expression profiles. However, due to the large variability in gene expression, identifying cell types based on the transcriptome remains challenging. ...

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Fine-mapping cellular QTLs with RASQUAL and ATAC-seq

When cellular traits are measured using high-throughput DNA sequencing, quantitative trait loci (QTLs) manifest as fragment count differences between individuals and allelic differences within individuals. Researchers from the Wellcome Trust Sanger Institute have developed RASQUAL (Robust Allele-Specific Quantitation and Quality Control), ...

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Making Single-Cell Biology Work

rna-seq

New Collaboration Between EMBL-EBI, the Wellcome Trust Sanger Institute and Fluidigm Keeps Research and Technology on the Cutting-Edge of Single-Cell Genomics December 17, 2014 06:24 AM Eastern Standard Time SOUTH SAN FRANCISCO, Calif. & HINXTON, U.K.–(BUSINESS WIRE)–A formal collaboration was ...

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