RNA-seq: Impact of RNA degradation on transcript quantification

May 30, 2014 Leave a comment 6,844 Views

The use of low quality RNA samples in whole-genome gene expression profiling remains controversial. It is unclear if transcript degradation in low quality RNA samples occurs uniformly, in which case the effects of degradation can be corrected via data normalization, ...

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RNA-seq: Impact of RNA degradation on transcript quantification

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